Project Snapshot
Prevention of Transmission Pillar
Identification Of Novel Group B Streptococcal Proteins Associated With Virulence.
Project Key Words: Group B Streptococcus, Virulence, Antibiotic Resistance
Principal Investigator: Gregory J. Tyrrell, PhD, FCCM, D(ABMM)
Project Theme: Innovation and Commercialization
The Aim
The project has two aims:
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Why is This Important?
GBS causes invasive disease in both adults and neonates; however, it is in the neonate that the invasive disease is the most devastating. Understanding the mechanisms involved in GBS pathogenesis will allow for novel targeted therapies to be developed.
Outcomes
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Research Questions
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Our Approach
Our approach will be three-fold:
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Leveraged Sources of Support
- Tyrrell - General Research Funds
- Provlab - in kind - GBS strains
- CFI - Tyrrell - Equipment
Knowledge & Technology: Exchange and Exploitation
- Input of funds will help in identifying potential new targets for preventing invasive GBS disease.
- In addition, funds will help in identifying whether antibiotic prophylaxis recommendations need to be readjusted in Alberta.
Highly Qualified Personnel
- Currently recruiting one full time PhD student.