Prevention of Transmission Pillar
Identification Of Novel Group B Streptococcal Proteins Associated With Virulence.
Project Key Words: Group B Streptococcus, Virulence, Antibiotic Resistance
Principal Investigator: Gregory J. Tyrrell, PhD, FCCM, D(ABMM)
Project Theme: Innovation and Commercialization
The project has two aims:
Why is This Important?
GBS causes invasive disease in both adults and neonates; however, it is in the neonate that the invasive disease is the most devastating. Understanding the mechanisms involved in GBS pathogenesis will allow for novel targeted therapies to be developed.
Our approach will be three-fold:
Leveraged Sources of Support
- Tyrrell - General Research Funds
- Provlab - in kind - GBS strains
- CFI - Tyrrell - Equipment
Knowledge & Technology: Exchange and Exploitation
- Input of funds will help in identifying potential new targets for preventing invasive GBS disease.
- In addition, funds will help in identifying whether antibiotic prophylaxis recommendations need to be readjusted in Alberta.
Highly Qualified Personnel
- Currently recruiting one full time PhD student.