CARB-X

Eligibility

Eligibility Criteria

• Definition of Eligibility:
  Applications must address an eligible Target Product Profile (TPP) or Preclinical Product Concept (PPC) and meet the minimal entry criteria for the current funding round.
  • EOI submissions should clearly demonstrate compliance with these criteria (non-confidential info).
  • Later stages require detailed supporting data under confidentiality agreements.
• Geographic Scope:
  No geographic restrictions; applications are welcome globally.
• Eligible Applicants:
  • Academic institutions and research hospitals worldwide are eligible.
  • No preference between industry and academia.
  • Applicants must show they have or can build the necessary expertise to execute the workplan.

Collaboration and Roles

• Collaborative Applications:
  Multiple entities can apply jointly, but:
  • One entity must be the primary applicant.
  • A single Principal Investigator (PI) must be named.
  • Contributions and management plans should be clearly described.
• Co-PIs:
  Not permitted.
• Multiple Applications:
  Applicants may participate in multiple applications with different roles (e.g., PI on one, collaborator on another).
  • Conflicts of interest and percent effort must be disclosed and managed.

Summary

Application process

The successful applicant will progress through the three-stage process outlined below. The application portal can be found at this LINK. 

Please note that successful applicants must contribute funding (“cost share”) equal to a percentage of the total cost of the agreed work package. Please refer to the FAQ document for additional information regarding cost share.

1. Non-confidential Expression of Interest (EOI)

• Fillable template for salient details of proposed project found at the following links:
  • Therapeutics for Infections
  • Diagnostics for Typhoid Fever in Low-Resource Settings
• Evaluated by CARB-X Research & Development Team for responsiveness
• Visit Apply Here to begin this process

2. Confidential project narrative and budget (“full proposal”)

• Fillable template for data-rich proposal, with several required attachments
• Low- and Middle-Income Country (LMIC)-focused programs might qualify for funding through the Official Development Assistance program
• Juried by a multidisciplinary external Advisory Board

3. Focused presentation to Advisory Board

• Short virtual presentation, followed by focused questions and answers
• Juried by a multidisciplinary external Advisory Board
• Recommendations made to CARB-X

Decisions on projects that will advance into negotiations to enter the CARB-X portfolio are made by the CARB-X Investment Committee (CIC).

Overhead

Foreign (non-US) applicants are not eligible to receive indirect costs. 

Application deadlines

RSO final internal review deadline

Program application deadline

NOTE: Consult your Faculty Associate Dean (Research) (ADR) regarding Faculty-specific deadlines and submission processes.

Principal Investigators: Complete a Research Management System (RMS) record, including a copy of your complete application, and submit this for approvals in RMS.

Postdocs, students, and trainees: For fellowships and externally-sponsored research training awards or opportunities, you must complete the Research Funding Application Approval (RFAA) Trainee PDF form, and submit it, along with a complete copy of the application, to Research Services at rsotrainee@ucalgary.ca. Trainees should not use RMS at this time.

Approvals: The University of Calgary requires that all funding applications be approved prior to submission. Approval requires signatures via either RMS or the RFAA Trainee form, in the following order:

• Principal Investigator
• Department Head
• Faculty ADR/Dean
• Research Services (on behalf of the Vice-President Research)

Read the Meaning of Grant Signatures policy to understand what your approval means. Please see the agency guidelines for details about which signatures are required on your application, as it may differ from internal requirements.

Late submissions: Late submissions will only be accepted in cases of medical or family emergencies, or other exceptional circumstances. If you submit your RMS record to Research Services after the internal deadline has passed, you must secure additional approvals. Please read: Late Applications Process.

RESOURCES

Public webinars will be held on 4 December and 5 December to discuss the scope of the funding round and application process, as well as share tips for submitting a good Expression of Interest. Webinar attendees will also have the opportunity to ask the CARB-X team questions.

Thursday, 4 December at 19:00 ET
Register here: bit.ly/4nwr4ES

Friday, 5 December at 09:00 ET
Register here: bit.ly/4ofT6We

RESEARCH SERVICES

Reminder: The sooner the researcher engages with Research Services, the more help we can be!

Contact the following Research Service units for support with:

Projects Involving Indigenous Research:

Support with incorporating wise practices in Indigenous research, community engagement, and Indigenous data management is available through the Indigenous Research Support Team (IRST).

Applicants can reach out by email to IRST at IRST@ucalgary.ca in advance of the RSO internal deadline. For more information about IRST, please visit the IRST webpage.

Knowledge Mobilization, Research Impact Assessment, DORA:

Support for knowledge mobilization/engagement/translation, community partnerships, research impact, responsible research assessment (DORA), and open science, is available through the Knowledge to Impact team.

Applicants can reach out by email to the KI team at knowledge.impact@ucalgary.ca.

For more information and access to resource archives, please visit the KI team webpage.

Research Data Management:

For information on research data management plans, processes, or best practices for your research program, please contact research.data@ucalgary.ca.

EDI in Research:

RSO can provide resources and support to research teams on the integration of equitable and inclusive practices in research design and research practice.

Contact edi.rso@ucalgary.ca for more information.

Research Security:

The Research Security Division is available to ensure researchers adhere to research security guidelines and policies, including the National Security Guidelines for Research Partnerships (NSGRP) and the policy on Sensitive Technology Research and Affiliations of Concern (STRAC).

Visit the Research Security website to learn more or contact researchsecurity@ucalgary.ca.

Pre-Award Submissions:

RMS: Creating a Pre-Award LOI
RMS: Creating a Pre-Award Application