Personalizing treatment targets for IGF-1 in Pediatric Growth Hormone Deficient Patients


Understanding how individual patients respond to treatment is the heart of personalized medicine. This study aims to understand how Insulin-like Growth Factor 1 (IGF-1), a marker of Growth Hormone function in the body, may be used to help determine how patients with Growth Hormone Deficiency are responding to treatment early on.


Currently recruiting participants: Yes

Eligible gender: Male, Female, Transgender, Other

Eligible ages: 1 to 18

Inclusion criteria:

This study is open to any patients from ages 1 to 18 who are diagnosed with Growth Hormone Deficiency or short stature.

Exclusion criteria:

1) Patients with kidney failure
2) Liver disease
3) Growth hormone resistance
4) Genetic syndromes that are known to be associated with short stature (e.g. Prader Willi or Turner Syndrome)


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Method of contact

Additional information

Contact information

Dennis Orton, PhD FCACB Clinical Assistant Professor | University of Calgary

Principal investigator:

Dennis Orton

Clinical trial: