Biomarkers and Mild Behavioural Impairment (BAMBI)


This study enrolls community dwelling older adults for assessments of cognition, behaviour, function, quality of life, and caregiver stress, in association with biomarkers, at 18 month intervals. Participants attend with a study partner, and at each visit are given a series of questionnaires and tests. The overall visit is ~2.5 hours in duration. Biomarkers of inflammation and neurodegeneration are obtained via a participant blood draw and urine collection at each visit. Additionally, participants will be given a stool collection kit to take home which will be returned to the lab for gut microbiome analysis.


Currently recruiting participants: Yes

Eligible gender: Male, Female, Transgender, Other

Eligible ages: 60 to 99

Accepts healthy participants: Yes

Inclusion criteria:

1. Age 60 or older with normal cognition, subjective cognitive decline, mild cognitive impairment, or mild AD dementia.
2. Study partner available who has known the participant for ≥5 years

Exclusion criteria:

1. Developmental disorders and neuropsychiatric conditions that would affect testing (e.g., autism, Huntington’s disease, schizophrenia, bipolar disorder)
2. Unable to provide informed consent
3. No study partner
4. Not fluent in English


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Method of contact

Additional information

Contact information

Ramnik Brar

Principal investigator:

Zahinoor Ismail

Clinical trial: