Brain in Motion II Study


The Brain In Motion 2 Study is examining the relationship between exercise, cerebral blood flow, and cognition in older adults who are at increased risk of Alzheimer’s Disease and related dementias and the role that exercise might play in the prevention of cognitive decline.

We are looking for 264 individuals to volunteer in an 18-month randomized controlled trial, which includes either a six-month aerobic exercise program, or a six-month stretch and strength program. All parking expenses, as well as access and supervised training at the University of Calgary, Mount Royal University, or 1-2 other community-based facilities will be covered by the study.


Currently recruiting participants: Yes

Eligible gender: Male, Female, Transgender, Other

Eligible ages: 50 to 80

Accepts healthy participants: Yes

Inclusion criteria:

1) The study is looking for participants who are sedentary. With one or more of the following:
a. A personal history of high blood pressure
b. A personal history of diabetes mellitus
c. Obesity
d. Elevated cholesterol
e. Current Smoker
f. Personal previous history of coronary artery disease
g. An immediate family member diagnosed with Alzheimer’s disease or dementia

(If you’re not sure about what your Fitness Level is, that’s okay; we can determine this through a telephone questionnaire conducted by one of our team members.)

2) In addition, the participants must have all of the following:
a. No history of dementia
b. Fluent in verbal and written English
c. No previous stroke or a mini-stroke (TIA)


This study is not currently accepting expressions of interest via the website. Please see contact information below.

Additional information

Contact information

Please contact the study coordinator at 403.210.7315 or by email at, or the Principal Investigator Dr. Marc Poulin at 403.220.8372 or at

Principal investigator:

Marc Poulin

Clinical trial: