Cognition and dementia biomarkers in bipolar disorder


Preliminary research suggests that bipolar disorder and certain types of dementia may be linked. Dementia-related changes are not well understood in bipolar disorder and are difficult to disentangle from the symptoms of bipolar disorder itself. This study is designed to uncover whether certain cognitive tests may be useful as screening tools for early detection of dementia in individuals with bipolar disorder. We are examining this by looking at the relationships between these cognitive tests, dementia biomarkers, and dementia-associated genes in individuals with bipolar disorder.

If you choose to participate, you will be asked to:
1) Complete a series of questionnaires and pen-and-paper tasks designed to assess your thinking skills;
2) Have your blood drawn to look for specific biomarkers of neurodegenerative disease.


Currently recruiting participants: Yes

Eligible gender: Male, Female, Transgender, Other

Eligible ages: 50 to 100

Inclusion criteria:

To participate in this study, you must:

1) Have a diagnosis of bipolar disorder
2) Currently have a stable, neutral mood
3) Be 50 years of age or older
4) Be fluent in written and oral English
5) Have normal or corrected-to-normal hearing and vision

Exclusion criteria:

You cannot participate in this study if you have:

1) Had a stroke or brain injury
2) Severe dementia


Fill out the following form if you want to participate in this research

Method of contact

Additional information

Contact information

Please contact Stephen (Ben) Peckham:

Principal investigator:

Brandy Callahan

Clinical trial: