Does cumulative oxygen desaturation or the nadir in saturation have a greater impact on the development of muscle fatigue.
Summary
We are conducting a research study to examine the role of oxygen in the development of muscle fatigue during exercise. Over a total of 5 visits you will perform bouts of cycling, one will be a maximal exercise test, one will be a familiarization session with a small amount of exercise and breathing some lower oxygen gases, and three sessions will be exercising till exhaustion. During two of the exercise to exhaustion tasks you will be given a slightly lower than normal amount of oxygen to breathe. During these sessions we will be giving you stimulations to your femoral nerve to measure your muscle fatigue and we will also be measuring your breathing and heart rate.
Eligibility
Eligible ages: 18 to 40
Accepts healthy participants: Yes
Inclusion criteria:
We are seeking healthy, recreationally active males and females age 18-40
Exclusion criteria:
-Obese individuals with a BMI>30 kg/m^2
-Someone currently smoking/vaping
-An individual with any cardiovascular, metabolic, respiratory diseases
-If you have any injuries that currently affects your ability to exercise
-If you are unable to commit to attending all sessions
-If you are pregnant, breast feeding, using a progesterone only birth control, or taking hormone replacement therapy
Participate
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Additional information
Contact information
Leah Mann
Principal investigator:
Paolo Dominelli
Clinical trial:
No
REB-ID:
REB24-1598