Genetics of cardiovascular disease


We are interested in finding the cause of diseases of the heart and blood vessels that first show up in children and young adults. Many of these diseases are inherited, but we still do not know the cause in most cases. This study will use genetic testing to find these causes, followed by experiments in the lab to look at these changes in detail to see how they may cause the heart or blood vessel disease.


Currently recruiting participants: Yes

Eligible gender: Male, Female, Transgender, Other

Accepts healthy participants: Yes

Inclusion criteria:

This study is open to all ages from newborns to adults. It involves not only the person with the heart or blood vessel disease but also their parents and other relatives in the family have the same or similar problem. You may take part in this study if you have one of these conditions:
1. You have heart that was not formed properly, also called congenital heart disease
2. You have a disease of the heart muscle (cardiomyopathy) that is not from another disease such as high blood pressure, diabetes, or heart valve problem or was caused by medications
3. You have a heart rhythm problem that is not from other diseases or medications
4. You have enlargement of the aorta that is not due to other diseases or hypermobile EHlers Danlos syndrome

Exclusion criteria:

You are not eligible if your heart or blood vessel disease is due to adult-onset diseases such as high blood pressure, diabetes, heart attack or is caused by environmental exposures (smoking, alcohol, drugs).


Fill out the following form if you want to participate in this research

Method of contact

Additional information

Contact information

Kim McBride, MD Department of Medical Genetics University of Calgary

Principal investigator:

Kim McBride

Clinical trial: