Mechanisms supporting Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder: A randomized, controlled clinical trial
Summary
The aim of this study is to determine if a single dose of psilocybin administered with motivational enhancement therapy (MET) can reduce heavy drinking in patients with an alcohol use disorder (AUD).
Eligible participants will be randomly allocated into either a high or low psilocybin dose group. All participant will be paired with a therapist and will receive up to 8 hours of preparation work prior to dosing. Following dosing participants will receive 5 weekly therapy sessions.
Clinical, behavioral and neuroimaging measures will be completed at various time points throughout the study.
Eligibility
Eligible ages: 22 to 65
Inclusion criteria:
- Aged 22-65
- Regularly consume alcohol and wish to decrease consumption
- Limited lifetime hallucinogen use
Exclusion criteria:
- Diagnosis of; schizophrenia, bipolar disorders, or active suicidal ideation
- Currently pregnant, nursing, or trying to become pregnant
Participate
Fill out the following form if you want to participate in this research
Collection of personal information
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Additional information
Contact information
If you are interested in applying for this study please complete the preliminary-screening form here: https://forms.office.com/r/KHvscxpnE2 OR contact pactlab@ucalgsry.ca if you have any questions.
Principal investigator:
Valerie Taylor
Clinical trial:
Yes
REB-ID:
REB23-0666
External links