We are doing a research study about children who have a problem with their circulation (blood flow) caused by an infection. This medical name for this situation is ‘septic shock’. Some people think that giving children lots of intravenous (IV) fluid is the best way to fix the circulation (blood flow) for children with septic shock, but other people worry that giving lots of IV fluid may cause problems for the patient. Another way to fix the circulation (blood flow) is to give less IV fluid and more medication. This research study will help us decide which is the best way to fix the circulation (blood flow) for children experiencing septic shock.


Currently recruiting participants: Yes

Eligible gender: Male, Female, Transgender, Other

Inclusion criteria:

1. Age 29 days to <18 year of age
2a. Patient has signs of septic shock which is showing in the patients blood flow, blood pressure or requiring certain medications
2b. The treating physician believe the patient may have septic shock
2c. The patient has already received a certain amount of fluid to try and correct the signs they are showing of suspected septic shock.

Exclusion criteria:

1. Patient admitted to the Neonatal Intensive Care Unit
2. Patient has a "Do Not Resuscitate" Order
3. Shock is caused by something other than sepsis.
4. Patient requires resuscitation in the Operating Room or Recovery Unit
5. Patient was previously enrolled in the study.


This study is not currently accepting expressions of interest via the website. Please see contact information below.

Additional information

Contact information

Recruitment is through hospital admission to the Alberta Children's Hospital

Principal investigator:

Simon Parsons

Clinical trial: