Team Grant: CIHR-JDRF Type 1 Diabetes Screening Research Consortium 2023

Eligibility

For an application to be eligible:

1. The Nominated Principal Applicant (NPA) must be an independent researcher affiliated with a Canadian postsecondary institution and/or its affiliated institutions (including hospitals, research institutes and other non-profit organizations with a mandate for health research and/or knowledge translation).
2. The NPA must have a substantive role in Canada for the duration of the requested grant term.
3. The Institution Paid by CIHR must be authorized to administer CIHR funds before the funding can be released. (for more information see Administration of Funds).
4. The Consortium must include a minimum of 3 inter-connected Research Teams; each to be led by an independent Principal Applicant (PA):
   • Acceptability
   • Feasibility
   • Follow-up and clinical monitoring

Each Research Team may undertake one or more research projects to address areas related to the focus of the Research Team. The NPA may lead one of the Research Teams.

5. Each Research Team must also include the following:
   • Early career researcher(s);
   • Knowledge user(s) which may include healthcare providers;
   • PWLE: In the context of this funding opportunity, this includes people at risk of or with T1D, and their families/informal caregivers, and/or patient groups representing these individuals.
   • For any research Teams involving First Nations, Inuit, Métis and/or Urban Indigenous populations, your team must include at least one applicant who self-identifies as Indigenous (First Nations, Inuit or Métis) or provides evidence of having meaningful and culturally safe involvement with Indigenous Peoples. A one-page document describing how they meet this requirement must be submitted as an "Other" attachment. (see How to Apply for more details).
6. The Consortium must include a Lead for each of the Cross-Cutting Themes who is identified as a Principal Applicant (PA) and/or a Principal Knowledge User (PKU):
   • Patient and Citizen Engagement
   • Knowledge Mobilization and Stakeholder Engagement
   • Data and Biosample Governance
   • Inclusion of Indigenous Peoples (First Nations, Inuit, Métis and Urban Indigenous communities)
   • Health Disparities and Equity, Diversity and Inclusion (EDI)
   • Sex- and Gender-Based Analysis + (SGBA+)

   Note that an individual, including the NPA or PA of a Research Team, can lead one or more Cross-Cutting Theme.

7. The NPA and the SGBA+ Lead must have successfully completed one of the sex- and gender-based analysis training modules available online through the CIHR Institute of Gender and Health and submit a Certificate of Completion by the application deadline. Select and complete the training module most applicable to your research project. Applicants are encouraged to review the "How to integrate sex and gender in research" section on the CIHR website.

Summary

The goal of the CIHR-JDRF Type 1 Diabetes Screening Research Consortium is to develop a single nationally coordinated research Consortium to explore key research questions pertaining to the feasibility and acceptability of a general population T1D screening program in Canada, building on experiences from other countries.

The Consortium will bring together experts from different disciplines with stakeholder organizations and people affected by T1D including, but not limited to, pediatric clinical endocrinology, T1D research, general population screening, health economics, health policy, representatives from First Nations, Inuit and Métis communities and health authorities/organizations, primary care provider associations, and people with lived experience (PWLE; i.e., people at risk of or with T1D, and their families and informal caregivers, or a patient organization representing these groups). PWLE must be meaningfully engaged in the Consortium, including in the Leadership and Governance of the Consortium and in all aspects of the research process, to ensure the Consortium undertakes its work in a way that is relevant to the T1D community.

The Consortium will ensure that research projects and other activities are well integrated and occur in alignment with common objectives and themes, maximizing opportunities to establish a coordinated approach to T1D screening in Canada. The Consortium should support coordination among Federal, Provincial and Territorial stakeholders to ensure that the research addresses relevant policy and operational questions that would need to be answered to develop an effective approach for general population screening for T1D in Canada.

This funding opportunity excludes research exclusively focused on screening of adults for T1D risk.

The specific objectives of this funding opportunity are to:

• Establish an interdisciplinary, inter-jurisdictional, and inter-sectoral National Type 1 Diabetes (T1D) Screening Research Consortium that aims to investigate the feasibility of T1D screening in the general population in Canada, building on the successes and experiences from other countries.
• Develop, implement, and evaluate research relevant to T1D screening that generates evidence to increase opportunities to identify pre-symptomatic T1D in the Canadian pediatric population, reduce the incidence of DKA at diagnosis, and improve outcomes for children and youth diagnosed with T1D, and their families.
• Support research that involves meaningful engagement with diverse stakeholders and PWLE, with particular attention to health disparities, Canada's diverse ethnocultural population and Indigenous Peoples' health and well-being.
• Build Canadian research capacity in the area of T1D screening.
• Maximize research impact and knowledge mobilization to inform health policy, decision making and planning; this includes the ethical, economic, legal and social aspects of T1D screening in the general population.

Application deadlines

RSO detailed review deadline

RSO final internal review deadline

Program application deadline

NOTE: Consult your Faculty Associate Dean (Research) (ADR) regarding Faculty-specific deadlines and submission processes.

Principal Investigators: Complete a Research Management System (RMS) record, including a copy of your complete application, and submit this for approvals in RMS.

Postdocs, students, and trainees: For fellowships and externally-sponsored research training awards or opportunities, you must complete the Research Funding Application Approval (RFAA) Trainee PDF form, and submit it, along with a complete copy of the application, to Research Services at rsotrainee@ucalgary.ca. Trainees should not use RMS at this time.

Approvals: The University of Calgary requires that all funding applications be approved prior to submission. Approval requires signatures via either RMS or the RFAA Trainee form, in the following order:

• Principal Investigator
• Department Head
• Faculty ADR/Dean
• Research Services (on behalf of the Vice-President Research)

Read the Meaning of Grant Signatures policy to understand what your approval means. Please see the agency guidelines for details about which signatures are required on your application, as it may differ from internal requirements.

Late submissions: Late submissions will only be accepted in cases of medical or family emergencies, or other exceptional circumstances. If you submit your RMS record to Research Services after the internal deadline has passed, you must secure additional approvals. Please read: Late Applications Process.

Overhead N/A

Webinar:

CIHR will be hosting webinar(s) to support participants with the requirements of this funding opportunity and to answer questions.

Date TBC

Submission Process:

Registration due directly to CIHR via ResearchNet by 6:00PM Calgary time on Wednesday, February 15, 2023. No RMS needed for this step.

Full application, plus approvals in RMS, will be required by RSO by noon on Thursday, March 9, 2023. Please be sure to select "Submitted for approvals" (Under Save & Progress) in RMS in enough time to allow for approvals from your Department Head and/or ADR prior to the internal RSO deadline. Consult your department and faculty for more information on their approval processes and timelines.

Do not submit through ResearchNet until RSO's signature has been granted!! 

Once institutional signature has been obtained, a copy of the CIHR signature page will be available via the RMS record, under Documents. Upload the CIHR signature page and routing slip in the Print/Upload Signature Pages task in ResearchNet by 6:00PM Calgary time on Tuesday, March 14, 2023.