"The MEMORI Study" – Imaging memory and cognition in dementia research.

Summary

This study wants to find a better way to identify people who have early signs of memory loss, trouble with thinking and decision-making, difficulty paying attention, and slower processing speed. The study enrolls community dwelling older adults for assessments of cognition, behaviour, function, quality of life, and caregiver stress, in association with biomarkers, at 6, 12 or 18 month intervals. Participants attend with a study partner, and at each visit are given a series of questionnaires and tests (the study partner will only be asked to answer the questionnaires). The overall visit is ~1.5 to -2.5 hours in duration. Non-invasive brain imaging (electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS)) will be used to record brain activity patterns. We will compare these patterns in healthy people, people with mild memory problems, and people with mild to moderate dementia. By understanding these patterns, we will create a way to detect memory problems sooner so people can get the proper treatment and support.

This study enrols community dwelling older adults for assessments of cognition, behaviour, function, quality of life, and caregiver stress, in association with biomarkers, at 18 month intervals. Participants attend with a study partner, and at each visit are given a series of questionnaires and tests. The overall visit is -2.5 hours in duration.