Apomorphine Effect on Pain in Parkinson's disease


Pain is a frequent symptom in Parkinson's disease. Pain is even present when medication is in effect. We hypothesize that apomorphine may be a safe, and useful treatment for patients with different pain subtypes in Parkinson's disease during off-times.


Currently recruiting participants: Yes

Eligible gender: Male, Female, Transgender, Other

Eligible ages: 18 to 70

Inclusion criteria:

- Patients with diagnosed Parkinson's disease
- Patients on antiparkinsonian medication and experiencing pain
- Patients who have not received apomorphine before or have not received any within the last six months

Exclusion criteria:

- Patients who can not report pain due to cognitive problems
- Patients associated with another medical condition, (e.g. any cardiovascular, renal or hepatic impairment, hematological or psychiatric diseases)
- Participants with poorly controlled orthostatic hypotension


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Method of contact

Additional information

Contact information

Research Assistant Beatrice Anghelescu bamanghe@ucalgary.ca 403-210-7542

Principal investigator:

Veronica Bruno

Clinical trial: